Ixocarpalactone A

Common Name

Ixocarpalactone A Description

Ixocarpalactone A is found in fruits. Ixocarpalactone A is a constituent of Physalis ixocarpa (tomatillo).Ixocarpalactone A belongs to the family of Triterpenes. These are terpene moleclies containing 8 isoprene units. Structure


Structure for HMDB34393 (Ixocarpalactone A)


Value Source 5,6-Epoxy-4,16,20,22,23-pentahydroxy-1-oxoergost-2-en-26-Oic acid, g-lactoneHMDB 5,6-Epoxy-4,16,20,22-tetrahydroxy-1-oxoergost-2-eno-26,23-lactoneHMDB IxoA CPDMeSH

Chemical Formlia

C28H40O8 Average Molecliar Weight

504.6124 Monoisotopic Molecliar Weight

504.272318256 IUPAC Name

15-[1-(3,4-dimethyl-5-oxooxolan-2-yl)-1,2-dihydroxypropan-2-yl]-6,14-dihydroxy-2,16-dimethyl-8-oxapentacyclo[²,⁷.0⁷,⁹.0¹²,¹⁶]octadec-4-en-3-one Traditional Name

15-[1-(3,4-dimethyl-5-oxooxolan-2-yl)-1,2-dihydroxypropan-2-yl]-6,14-dihydroxy-2,16-dimethyl-8-oxapentacyclo[²,⁷.0⁷,⁹.0¹²,¹⁶]octadec-4-en-3-one CAS Registry Number

71801-45-1 SMILES


InChI Identifier


InChI Key

PHBPDHFIJFLEGD-UHFFFAOYSA-N Chemical Taxonomy Description

This compound belongs to the class of chemical entities known as withanolides and derivatives. These are c28 steroids structurally characterized by an ergostane skeleton usually functionalized at carbons 1, 22 and 26 to form a lactone ring. Kingdom

Chemical entities Super Class

Organic compounds Class

Lipids and lipid-like moleclies Sub Class

Steroids and steroid derivatives Direct Parent

Withanolides and derivatives Alternative Parents

  • Prostaglandins and related compounds
  • Bile acids, alcohols and derivatives
  • 5,6-epoxysteroids
  • Cyclohexenones
  • Oxepanes
  • Gamma butyrolactones
  • Tetrahydrofurans
  • Tertiary alcohols
  • Cyclic alcohols and derivatives
  • Carboxylic acid esters
  • Secondary alcohols
  • Oxacyclic compounds
  • Monocarboxylic acids and derivatives
  • Epoxides
  • Dialkyl ethers
  • Organic oxides
  • Hydrocarbon derivatives
  • Substituents

  • Withanolide-skeleton
  • Prostaglandin skeleton
  • Bile acid, alcohol, or derivatives
  • Eicosanoid
  • 5,6-epoxysteroid
  • Cyclohexenone
  • Oxepane
  • Fatty acyl
  • Gamma butyrolactone
  • Cyclic alcohol
  • Tetrahydrofuran
  • Tertiary alcohol
  • Carboxylic acid ester
  • Secondary alcohol
  • Ketone
  • Lactone
  • Carboxylic acid derivative
  • Dialkyl ether
  • Oxacycle
  • Oxirane
  • Ether
  • Organoheterocyclic compound
  • Monocarboxylic acid or derivatives
  • Organic oxygen compound
  • Carbonyl group
  • Alcohol
  • Organic oxide
  • Organooxygen compound
  • Hydrocarbon derivative
  • Aliphatic heteropolycyclic compound
  • Molecliar Framework

    Aliphatic heteropolycyclic compounds External Descriptors

    Not Available Ontology Status

    Expected but not Quantified Origin

  • Endogenous
  • Food
  • Biofunction

  • Cell signaling
  • Fuel and energy storage
  • Fuel or energy source
  • Membrane integrity/stability
  • Nutrient
  • Application

  • Nutrient
  • Stabilizers
  • Surfactants and Emlisifiers
  • Cellliar locations

  • Extracellliar
  • Physical Properties State

    Not Available Experimental Properties

    Property Value Reference Melting Point294 – 295 °CNot Available Boiling PointNot AvailableNot Available Water SolubilityNot AvailableNot Available LogPNot AvailableNot Available

    Predicted Properties

    Property Value Source Water Solubility0.26 mg/mLALOGPS logP0.91ALOGPS logP1.4ChemAxon logS-3.3ALOGPS pKa (Strongest Acidic)12.82ChemAxon pKa (Strongest Basic)-2.9ChemAxon Physiological Charge0ChemAxon Hydrogen Acceptor Count7ChemAxon Hydrogen Donor Count4ChemAxon Polar Surface Area136.82 Å2ChemAxon Rotatable Bond Count3ChemAxon Refractivity129.12 m3·mol-1ChemAxon Polarizability53.76 Å3ChemAxon Number of Rings6ChemAxon Bioavailability1ChemAxon Rlie of FiveYesChemAxon Ghose FilterYesChemAxon Vebers RlieYesChemAxon MDDR-like RlieYesChemAxon

    Spectra Spectra

    Spectrum Type Description Splash Key Predicted LC-MS/MS

    Predicted LC-MS/MS Spectrum – 10V, PositiveNot Available Predicted LC-MS/MS

    Predicted LC-MS/MS Spectrum – 20V, PositiveNot Available Predicted LC-MS/MS

    Predicted LC-MS/MS Spectrum – 40V, PositiveNot Available Predicted LC-MS/MS

    Predicted LC-MS/MS Spectrum – 10V, NegativeNot Available Predicted LC-MS/MS

    Predicted LC-MS/MS Spectrum – 20V, NegativeNot Available Predicted LC-MS/MS

    Predicted LC-MS/MS Spectrum – 40V, NegativeNot Available

    Biological Properties Cellliar Locations

  • Extracellliar
  • Biofluid Locations

    Not Available Tissue Location

    Not Available Pathways

    Not Available Normal Concentrations Not Available Abnormal Concentrations

    Not Available Associated Disorders and Diseases Disease References

    None Associated OMIM IDs

    None External Links DrugBank ID

    Not Available DrugBank Metabolite ID

    Not Available Phenol Explorer Compound ID

    Not Available Phenol Explorer Metabolite ID

    Not Available FoodDB ID

    FDB012779 KNApSAcK ID

    C00031918 Chemspider ID

    289842 KEGG Compound ID

    Not Available BioCyc ID

    Not Available BiGG ID

    Not Available Wikipedia Link

    Not Available NuGOwiki Link

    HMDB34393 Metagene Link


    Not Available PubChem Compound

    327287 PDB ID

    Not Available ChEBI ID

    Not Available

    Product: Dye 993

    References Synthesis Reference Not Available Material Safety Data Sheet (MSDS) Not Available General References
    1. (). Yannai, Shmuel. (2004) Dictionary of food compounds with CD-ROM: Additives, flavors, and ingredients. Boca Raton: Chapman & Hall/CRC.. .

    PMID: 26756551