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LR ligands. IL-1b and especially poly significantly enhanced CD55 expression in FLS from RA and OA. In contrast, CD55 was not upregulated in dermal fibroblasts by any of the tested…

Type Culture Collection and maintained in Dulbecco's modified Eagle medium containing 10% fetal bovine serum and antibiotics & antimycotics. Plasmids construction Two vectors were utilized that encoded either the cytomegalovirus…

solution to a final concentration of 20 nM prior to blotting. A commercial b-catenin antibody was used for comparison at 1:2000 dilution. The phospho-S33/S37/T41 bcatenin antibody was used at dilution…

uoles containing neutral lipids. The number of differentiated adipocytes in culture increased in the presence of 10 or 100 mM nicotinamide. To test whether activation of Sirt-1 inhibits adipogenesis during…

om tubes was centrifuged at 3006g " 23977191 for 5 min, and the pellet of motile sperm was washed once. The final concentration of spermatozoa was roughly adjusted to 16106…

n were barely detectable and GLT1 mRNA was virtually absent. To establish whether EAAC1 was the transporter subtype mediating stimulation of glutamate-induced metabolism, we investigated the effect of selective EAAC1…

oniae CpxR very likely binds to DNA, given its sequence homology to other effector domains that have this function. A multiple sequence alignment of the proteins clearly showed that they…

ing the fact that there was no significant difference in free Heme level between CXC102/2 infected mice and non-infected controls, we postulated that HO-1 activation may not be required under…

mmon feature for both biomacromolecules and small-molecules in nature and in our daily life. Biomacromolecules have the potential to stereoselectively recognize and dispose the ligands. For example, it has been…

rine leiomyoma as well as identify potential therapeutic targets. Because DNA methylation is reversible, epigenetic modifying drugs could be used in the medical management of uterine leiomyoma. Importantly, aberrant DNA…