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D mutations identified in this study are in blue. `*' denotes residues that are identical in all sequences, `:' denotes conserved substations and `.' indicates semi-conserved substitutions. doi:10.1371/journal.pone.0067197.gFigure 3. Activity…

Derived amyloid fibrils to act as nuclei for the polymerization of full-length PrP would shed light upon the relative importance of different regions as cores for PrP amyloid formation. In…

In GMGE cells transfected with pcDNA3.1-GLUT1 and pcDNA3.1-GLUT12 simultaneously, which may be attributed to that GLUT1 was mainly distributed in cell membrane, while GLUT12 was always expressed in endoplasmic reticulum…

onist. Quantification of Ca2 spike frequency of co-stimulated CMs with a constant concentration of nonanoic acid and a rising concentration of the antagonist in Ca2 imaging experiments. The data are…

S were transfected with pshRNA-UBE2D3 and negative control. Samples were collected at the indicated time points and fixed in 70 ethanol overnight. For cell cycle analysis, fixed cells 10781694 were…

the presence of blasticidin and G418. All the transformants were screened by PCR and further confirmed by RTPCR and Northern blot hybridization.Yeast two-hybrid interactions For bait constructs, protein coding regions…

Eas green bars represent genes whose transcripts were detected at ,103 copies/ml. Error bars represent the standard error of the mean calculated using data from all tested NP samples. doi:10.1371/journal.pone.0067147.gExpression…

classical monocytes, or of a combination of both injury and hampered tissue repair, remains unclear. Endothelial cells play a crucial role by releasing multiple inflammatory mediators and expressing various adhesion…

n the heart development in the earlier embryonic stage remains an interesting question for further investigation. Heart growth occurs by one of two methods, hyperplasia or hypertrophy, and fetal glucocorticoid…

by our previous investigation of purinergic modulation of the murine locomotor CPG. 12 / 17 Modulation of Spinal Motor Networks by Glia Stimulation of glia does not influence the frequency…