Product Name :
PD-1/PD-L1-IN-8
Description:
PD-1/PD-L1-IN-8 (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.
CAS:
2230911-59-6
Molecular Weight:
693.79
Formula:
C41H39N7O4
Chemical Name:
(3R)-1-[(7-cyano-2-{3′-[(3-{[(3R)-3-hydroxypyrrolidin-1-yl]methyl}-1,7-naphthyridin-8-yl)amino]-2,2′-dimethyl-[1,1′-biphenyl]-3-yl}-1,3-benzoxazol-5-yl)methyl]pyrrolidine-3-carboxylic acid
Smiles :
CC1C(=CC=CC=1C1=NC2=CC(CN3C[C@@H](CC3)C(O)=O)=CC(C#N)=C2O1)C1C=CC=C(NC2=NC=CC3=CC(CN4C[C@H](O)CC4)=CN=C32)C=1C
InChiKey:
QARLNMDDSQMINK-BVRKHOPBSA-N
InChi :
InChI=1S/C41H39N7O4/c1-24-32(5-3-7-34(24)40-46-36-17-26(15-30(18-42)38(36)52-40)20-47-13-10-29(22-47)41(50)51)33-6-4-8-35(25(33)2)45-39-37-28(9-12-43-39)16-27(19-44-37)21-48-14-11-31(49)23-48/h3-9,12,15-17,19,29,31,49H,10-11,13-14,20-23H2,1-2H3,(H,43,45)(H,50,51)/t29-,31-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PD-1/PD-L1-IN-8 (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 Product information|CAS Number: 2230911-59-6|Molecular Weight: 693.79|Formula: C41H39N7O4|Chemical Name: (3R)-1-[(7-cyano-2-{3′-[(3-{[(3R)-3-hydroxypyrrolidin-1-yl]methyl}-1,7-naphthyridin-8-yl)amino]-2,2′-dimethyl-[1,1′-biphenyl]-3-yl}-1,3-benzoxazol-5-yl)methyl]pyrrolidine-3-carboxylic acid|Smiles: CC1C(=CC=CC=1C1=NC2=CC(CN3C[C@@H](CC3)C(O)=O)=CC(C#N)=C2O1)C1C=CC=C(NC2=NC=CC3=CC(CN4C[C@H](O)CC4)=CN=C32)C=1C|InChiKey: QARLNMDDSQMINK-BVRKHOPBSA-N|InChi: InChI=1S/C41H39N7O4/c1-24-32(5-3-7-34(24)40-46-36-17-26(15-30(18-42)38(36)52-40)20-47-13-10-29(22-47)41(50)51)33-6-4-8-35(25(33)2)45-39-37-28(9-12-43-39)16-27(19-44-37)21-48-14-11-31(49)23-48/h3-9,12,15-17,19,29,31,49H,10-11,13-14,20-23H2,1-2H3,(H,43,45)(H,50,51)/t29-,31-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{S1p receptor agonist 1} medchemexpress|{S1p receptor agonist 1} LPL Receptor|{S1p receptor agonist 1} Protocol|{S1p receptor agonist 1} In stock|{S1p receptor agonist 1} custom synthesis|{S1p receptor agonist 1} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Ixazomib} MedChemExpress|{Ixazomib} Proteasome|{Ixazomib} Biological Activity|{Ixazomib} Data Sheet|{Ixazomib} manufacturer|{Ixazomib} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23329319 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|