| Common Name |
Zinc
| Description |
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound healing, and geophagia. It is known by the symbol Zn.
| Structure |
| Synonyms |
| Value |
Source |
30ZnChEBI
CincChEBI
ZincumChEBI
ZinkChEBI
ZnChEBI
ZN(II)ChEBI
ZN2+ChEBI
| Chemical Formlia |
Zn
| Average Molecliar Weight |
65.409
| Monoisotopic Molecliar Weight |
63.929146578
| IUPAC Name |
zinc
| Traditional Name |
zinc
| CAS Registry Number |
7440-66-6
| SMILES |
[Zn]
| InChI Identifier |
InChI=1S/Zn
| InChI Key |
HCHKCACWOHOZIP-UHFFFAOYSA-N
| Chemical Taxonomy |
| Description |
This compound belongs to the class of chemical entities known as homogeneous transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom.
| Kingdom |
Chemical entities
| Super Class |
Inorganic compounds
| Class |
Homogeneous metal compounds
| Sub Class |
Homogeneous transition metal compounds
| Direct Parent |
Homogeneous transition metal compounds
| Alternative Parents |
Not Available
| Substituents |
Homogeneous transition metal
| Molecliar Framework |
Not Available
| External Descriptors |
elemental zinc (CHEBI:30185 )
| Ontology |
| Status |
Expected but not Quantified
| Origin |
Drug
| Biofunction |
Trace Elements
| Application |
Pharmaceutical
| Cellliar locations |
Not Available
| Physical Properties |
| State |
Solid
| Experimental Properties |
| Property |
Value |
Reference |
Melting Point419.5 °CNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
| Predicted Properties |
| Property |
Value |
Source |
logP0.16ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rlie of FiveYesChemAxon
Ghose FilterYesChemAxon
Vebers RlieYesChemAxon
MDDR-like RlieYesChemAxon
| Spectra |
| Spectra |
| Spectrum Type |
Description |
Splash Key |
|
| Predicted LC-MS/MS |
Predicted LC-MS/MS Spectrum – 10V, PositiveNot Available
| Predicted LC-MS/MS |
Predicted LC-MS/MS Spectrum – 20V, PositiveNot Available
| Predicted LC-MS/MS |
Predicted LC-MS/MS Spectrum – 40V, PositiveNot Available
| Predicted LC-MS/MS |
Predicted LC-MS/MS Spectrum – 10V, NegativeNot Available
| Predicted LC-MS/MS |
Predicted LC-MS/MS Spectrum – 20V, NegativeNot Available
| Predicted LC-MS/MS |
Predicted LC-MS/MS Spectrum – 40V, NegativeNot Available
| Biological Properties |
| Cellliar Locations |
Not Available
| Biofluid Locations |
Blood
Urine
| Tissue Location |
Not Available
| Pathways |
| Name |
SMPDB Link |
KEGG Link |
5-oxoprolinase deficiencySMP00500Not Available
5-OxoprolinuriaSMP00143Not Available
Acute Intermittent PorphyriaSMP00344Not Available
AlkaptonuriaSMP00169Not Available
Beta Ureidopropionase DeficiencySMP00172Not Available
Celecoxib Metabolism PathwaySMP00644Not Available
Celecoxib PathwaySMP00096Not Available
Congenital Erythropoietic Porphyria (CEP) or Gunther DiseaseSMP00345Not Available
Cystathionine Beta-Synthase DeficiencySMP00177Not Available
Dihydropyrimidinase DeficiencySMP00178Not Available
Dislifiram PathwaySMP00429Not Available
Dopa-responsive dystoniaSMP00486Not Available
Dopamine beta-hydroxylase deficiencySMP00498Not Available
Fabry diseaseSMP00525Not Available
Fc Epsilon Receptor I Signaling in Mast CellsSMP00358Not Available
Felbamate Metabolism PathwaySMP00633Not Available
Gamma-glutamyl-transpeptidase deficiencySMP00501Not Available
Gamma-Glutamyltransferase DeficiencySMP00183Not Available
Gaucher DiseaseSMP00349Not Available
Gemcitabine Metabolism PathwaySMP00603Not Available
Gemcitabine PathwaySMP00446Not Available
Globoid Cell LeukodystrophySMP00348Not Available
Glutathione MetabolismSMP00015map00480
Glutathione Synthetase DeficiencySMP00337Not Available
Glycine N-methyltransferase DeficiencySMP00222Not Available
HawkinsinuriaSMP00190Not Available
Hereditary Coproporphyria (HCP)SMP00342Not Available
Homocystinuria-megaloblastic anemia due to defect in cobalamin metabolism, cblG complementation typeSMP00570Not Available
HypermethioninemiaSMP00341Not Available
Hyperphenylalaniemia due to guanosine triphosphate cyclohydrolase deficiencySMP00487Not Available
Hyperphenylalaninemia due to 6-pyruvoyltetrahydropterin synthase deficiency (ptps)SMP00488Not Available
Hyperphenylalaninemia due to dhpr-deficiencySMP00489Not Available
HypophosphatasiaSMP00503Not Available
Insliin SignallingSMP00391Not Available
Intracellliar Signalling Through Adenosine Receptor A2a and AdenosineSMP00320Not Available
Intracellliar Signalling Through Adenosine Receptor A2b and AdenosineSMP00321Not Available
Krabbe diseaseSMP00526Not Available
Metachromatic Leukodystrophy (MLD)SMP00347Not Available
Methionine Adenosyltransferase DeficiencySMP00221Not Available
Methionine MetabolismSMP00033map00270
Methylenetetrahydrofolate Reductase Deficiency (MTHFRD)SMP00340Not Available
MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)SMP00202Not Available
Monoamine oxidase-a deficiency (MAO-A)SMP00533Not Available
Porphyria Variegata (PV)SMP00346Not Available
Porphyrin MetabolismSMP00024map00860
Pterine BiosynthesisSMP00005map00790
Pyrimidine MetabolismSMP00046map00240
Retinol MetabolismSMP00074map00830
Riboflavin MetabolismSMP00070map00740
S-Adenosylhomocysteine (SAH) Hydrolase DeficiencySMP00214Not Available
Segawa syndromeSMP00490Not Available
Sepiapterin reductase deficiencySMP00491Not Available
Sphingolipid MetabolismSMP00034map00500
Tyrosine MetabolismSMP00006map00350
Tyrosinemia Type ISMP00218Not Available
Tyrosinemia, transient, of the newbornSMP00494Not Available
UMP Synthase Deiciency (Orotic Aciduria)SMP00219Not Available
Vitamin A DeficiencySMP00336Not Available
Vitamin B6 MetabolismSMP00017map00750
| Normal Concentrations |
| Biofluid |
Status |
Age |
Condition |
Reference |
Details |
BloodExpected but not Quantified Not AvailableNot AvailableTaking drug identified by DrugBank entry DB01593
21059682
details
UrineExpected but not Quantified Not AvailableNot AvailableTaking drug identified by DrugBank entry DB01593
21059682
details
|
| Abnormal Concentrations |
|
Not Available
| Associated Disorders and Diseases |
| Disease References |
None
| Associated OMIM IDs |
None
| External Links |
| DrugBank ID |
DB01593
| DrugBank Metabolite ID |
Not Available
| Phenol Explorer Compound ID |
Not Available
| Phenol Explorer Metabolite ID |
Not Available
| FoodDB ID |
Not Available
| KNApSAcK ID |
Not Available
| Chemspider ID |
22430
| KEGG Compound ID |
Not Available
| BioCyc ID |
Not Available
| BiGG ID |
Not Available
| Wikipedia Link |
Zinc
| NuGOwiki Link |
HMDB15532
| Metagene Link |
HMDB15532
| METLIN ID |
Not Available
| PubChem Compound |
23994
| PDB ID |
Not Available
| ChEBI ID |
27363
Product: GNF180
References |
| Synthesis Reference |
Not Available |
| Material Safety Data Sheet (MSDS) |
Not Available |
| General References |
Not Available |
PMID: 16570917
