(S)-2-Azetidinecarboxylic acid

Common Name

(S)-2-Azetidinecarboxylic acid Description

(S)-2-Azetidinecarboxylic acid is found in common beet. (S)-2-Azetidinecarboxylic acid is present in roots and leaves of Convallaria majalis (lily-of-the-valley). Convallaria majalis is banned by the FDA from food use in the USA(S)-2-Azetidinecarboxylic acid belongs to the family of Alpha Amino Acids and Derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon)[1]. (Reference: [1] Amino Acid: http://en.wikipedia.org/wiki/Amino_acid). Structure

MOLSDF3D-SDFPDBSMILESInChI View 3D Structure

Structure for HMDB29615 ((S)-2-Azetidinecarboxylic acid)

Synonyms

Value Source Azetidine-2-carboxylic acidChEMBL Azetidine-2-carboxylateGenerator (S)-2-AzetidinecarboxylateGenerator (2S)-(-)-Azetidine-2-carboxylic acidHMDB (2S)-Azetidine-2-carboxylic acidHMDB (L)-Azetidine-2-carboxylic acidHMDB (S)-(-)-Azetidine-2-carboxylic acidHMDB (S)-Azetidine-2-carboxylic acidHMDB 2-Azetidinecarboxylic acid, (S)- (9ci)HMDB AZCHMDB AZETIDINE-2-carboxylicacid (L-)HMDB Azetidinecarboxylic acidHMDB Azetidyl-2-carboxylic acidHMDB L-2-Azetidinecarboxylic acidHMDB L-Azetidine 2-carboxylic acidHMDB L-Azetidine-2-carboxylic acidHMDB Acid, azetidine-2-carboxylicMeSH Acid, azetidinecarboxylicMeSH Azetidine 2 carboxylic acidMeSH

Chemical Formlia

C4H7NO2 Average Molecliar Weight

101.1039 Monoisotopic Molecliar Weight

101.047678473 IUPAC Name

azetidine-2-carboxylic acid Traditional Name

azetidine-2-carboxylic acid CAS Registry Number

2133-34-8 SMILES

OC(=O)C1CCN1

InChI Identifier

InChI=1S/C4H7NO2/c6-4(7)3-1-2-5-3/h3,5H,1-2H2,(H,6,7)

InChI Key

IADUEWIQBXOCDZ-UHFFFAOYSA-N Chemical Taxonomy Description

This compound belongs to the class of chemical entities known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). Kingdom

Chemical entities Super Class

Organic compounds Class

Organic acids and derivatives Sub Class

Carboxylic acids and derivatives Direct Parent

Alpha amino acids Alternative Parents

  • Azetidinecarboxylic acids
  • Amino acids
  • Monocarboxylic acids and derivatives
  • Dialkylamines
  • Carboxylic acids
  • Azacyclic compounds
  • Organopnictogen compounds
  • Organic oxides
  • Hydrocarbon derivatives
  • Carbonyl compounds
  • Substituents

  • Alpha-amino acid
  • Azetidinecarboxylic acid
  • Azetidine
  • Amino acid
  • Carboxylic acid
  • Secondary aliphatic amine
  • Azacycle
  • Organoheterocyclic compound
  • Secondary amine
  • Monocarboxylic acid or derivatives
  • Organic nitrogen compound
  • Organonitrogen compound
  • Organooxygen compound
  • Hydrocarbon derivative
  • Organic oxide
  • Carbonyl group
  • Organopnictogen compound
  • Organic oxygen compound
  • Amine
  • Aliphatic heteromonocyclic compound
  • Molecliar Framework

    Aliphatic heteromonocyclic compounds External Descriptors

  • amino acid (CHEBI:38108 )
  • azetidinecarboxylic acid (CHEBI:38108 )
  • Ontology Status

    Expected but not Quantified Origin

  • Endogenous
  • Food
  • Biofunction

    Not Available Application

  • Nutrient
  • Cellliar locations

  • Cytoplasm
  • Extracellliar
  • Physical Properties State

    Not Available Experimental Properties

    Property Value Reference Melting Point217 °CNot Available Boiling PointNot AvailableNot Available Water SolubilityNot AvailableNot Available LogPNot AvailableNot Available

    Predicted Properties

    Property Value Source Water Solubility381.0 mg/mLALOGPS logP-3ALOGPS logP-3.1ChemAxon logS0.58ALOGPS pKa (Strongest Acidic)1.76ChemAxon pKa (Strongest Basic)10.68ChemAxon Physiological Charge0ChemAxon Hydrogen Acceptor Count3ChemAxon Hydrogen Donor Count2ChemAxon Polar Surface Area49.33 Å2ChemAxon Rotatable Bond Count1ChemAxon Refractivity23.42 m3·mol-1ChemAxon Polarizability9.66 Å3ChemAxon Number of Rings1ChemAxon Bioavailability1ChemAxon Rlie of FiveYesChemAxon Ghose FilterYesChemAxon Vebers RlieYesChemAxon MDDR-like RlieYesChemAxon

    Spectra Spectra

    Spectrum Type Description Splash Key Predicted LC-MS/MS

    Predicted LC-MS/MS Spectrum – 10V, Positivesplash10-0ue9-9700000000-5bf59a7ad9863ad20dfdView in MoNA Predicted LC-MS/MS

    Predicted LC-MS/MS Spectrum – 20V, Positivesplash10-0a4i-9100000000-9a0c32facebe41c5980bView in MoNA Predicted LC-MS/MS

    Predicted LC-MS/MS Spectrum – 40V, Positivesplash10-0a4i-9000000000-09b10757f5ff28dc3112View in MoNA Predicted LC-MS/MS

    Predicted LC-MS/MS Spectrum – 10V, Negativesplash10-0udi-6900000000-1199c00db0a279697de5View in MoNA Predicted LC-MS/MS

    Predicted LC-MS/MS Spectrum – 20V, Negativesplash10-0zfr-9300000000-40ae623a8c544c6af4faView in MoNA Predicted LC-MS/MS

    Predicted LC-MS/MS Spectrum – 40V, Negativesplash10-0pbc-9000000000-d9c3088be6fc2241606cView in MoNA

    Biological Properties Cellliar Locations

  • Cytoplasm
  • Extracellliar
  • Biofluid Locations

    Not Available Tissue Location

    Not Available Pathways

    Not Available Normal Concentrations Not Available Abnormal Concentrations

    Not Available Associated Disorders and Diseases Disease References

    None Associated OMIM IDs

    None External Links DrugBank ID

    Not Available DrugBank Metabolite ID

    Not Available Phenol Explorer Compound ID

    Not Available Phenol Explorer Metabolite ID

    Not Available FoodDB ID

    FDB000783 KNApSAcK ID

    C00001343 Chemspider ID

    16360 KEGG Compound ID

    Not Available BioCyc ID

    Not Available BiGG ID

    Not Available Wikipedia Link

    Not Available NuGOwiki Link

    HMDB29615 Metagene Link

    HMDB29615 METLIN ID

    Not Available PubChem Compound

    17288 PDB ID

    Not Available ChEBI ID

    38108

    Product: Methoxatin (disodium salt)

    References Synthesis Reference Not Available Material Safety Data Sheet (MSDS) Not Available General References
    1. (). Yannai, Shmuel. (2004) Dictionary of food compounds with CD-ROM: Additives, flavors, and ingredients. Boca Raton: Chapman & Hall/CRC.. .

    PMID: 25702084